9E9U

Vanadate-bound Putative Ancestral Protein Tyrosine Phosphatase ShufPTP - Highest p-loop Conformation

Summary for 9E9U

Entry DOI	10.2210/pdb9e9u/pdb
Descriptor	ShufPTP, VANADATE ION (3 entities in total)
Functional Keywords	phosphatase, inhibitor, asr, cso, ocs, oxidized cystine, hydrolase
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	17576.12
Authors	Denson, J.M.,Shen, R.,Hengge, A.C.,Johnson, S.J. (deposition date: 2024-11-08, release date: 2024-12-11, Last modification date: 2025-12-24)
Primary citation	Yehorova, D.,Alansson, N.,Shen, R.,Denson, J.M.,Robinson, M.,Risso, V.A.,Ramirez Molina, N.,Loria, J.P.,Gaucher, E.A.,Sanchez-Ruiz, J.M.,Hengge, A.C.,Johnson, S.J.,Kamerlin, S.C.L. Conformational Dynamics and Catalytic Backups in a Hyper-thermostable Engineered Archaeal Protein Tyrosine Phosphatase Jacs Au, 2025 Cited by DOI: 10.1021/jacsau.5c00756 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation