9E9L

Vanadate-bound Putative Ancestral Protein Tyrosine Phosphatase ShufPTP - Intermediate p-loop Conformation

Summary for 9E9L

• Entry DOI: 10.2210/pdb9e9l/pdb
• Descriptor: ShufPTP, SULFATE ION, VANADATE ION, ... (5 entities in total)
• Functional Keywords: phosphatase, inhibitor, asr, cso, oxidized cystine, hydrolase
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 17828.34

Authors

Denson, J.M.,Shen, R.,Hengge, A.C.,Johnson, S.J. (deposition date: 2024-11-08, release date: 2024-12-11, Last modification date: 2025-12-24)

• Primary citation: Yehorova, D.,Alansson, N.,Shen, R.,Denson, J.M.,Robinson, M.,Risso, V.A.,Ramirez Molina, N.,Loria, J.P.,Gaucher, E.A.,Sanchez-Ruiz, J.M.,Hengge, A.C.,Johnson, S.J.,Kamerlin, S.C.L.; Conformational Dynamics and Catalytic Backups in a Hyper-thermostable Engineered Archaeal Protein Tyrosine Phosphatase; Jacs Au, 2025; DOI: 10.1021/jacsau.5c00756

Experimental method

X-RAY DIFFRACTION (2.1 Å)