9E8R

X-ray structure of SARS-CoV-2 main protease T190I covalently bound to compound GRL-051-22 at 1.5 A

This is a non-PDB format compatible entry.

Summary for 9E8R

• Entry DOI: 10.2210/pdb9e8r/pdb
• Descriptor: 3C-like proteinase nsp5, (3S)-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-2-[3-methyl-N-(trifluoroacetyl)-L-valyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, SODIUM ION, ... (4 entities in total)
• Functional Keywords: main protease, 3-chymotrypsin-like protease, mpro, 3clpro, structural genomics, center for structural biology of infectious diseases, csbid, viral protein, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus
• Total number of polymer chains: 1
• Total formula weight: 34384.14

Authors

Beechboard, S.N.,Mesecar, A.D.,Ghosh, A.K.,Center for Structural Biology of Infectious Diseases (CSBID) (deposition date: 2024-11-06, release date: 2025-11-26)

• Primary citation: Beechboard, S.N.,Mesecar, A.D.,Ghosh, A.K.,Center for Structural Biology of Infectious Diseases (CSBID); X-ray structure of SARS-CoV-2 main protease T190I covalently bound to compound GRL-051-22 at 1.5 A.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)