9E4I

Human ASIC1a at pH 7.5 in complex with MitTx

Summary for 9E4I

• Entry DOI: 10.2210/pdb9e4i/pdb
• EMDB information: 47511
• Descriptor: Acid-sensing ion channel 1, Kunitz-type neurotoxin MitTx-alpha, Basic phospholipase A2 homolog MitTx-beta (3 entities in total)
• Functional Keywords: ion channel, trimer, toxin, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 243414.74

Authors

Hartfield, K.A.,Yoshioka, C.,Cahill, J.,Baconguis, I. (deposition date: 2024-10-24, release date: 2026-01-21)

• Primary citation: Cahill, J.,Hartfield, K.A.,Heusser, S.A.,Ritter, N.,Poulsen, M.H.,Yoshioka, C.,Pless, S.A.,Baconguis, I.; Conformational plasticity of human acid-sensing ion channel 1a; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.33 Å)