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9E2Q

Cryo-EM structure of DNMT 3A2/3B3 tetramer in complex with a di-nucleosome with a six base pair linker

Summary for 9E2Q
Entry DOI10.2210/pdb9e2q/pdb
Related9E00 9E05
EMDB information47461
DescriptorHistone H3.2, S-ADENOSYL-L-HOMOCYSTEINE, Histone H4, ... (10 entities in total)
Functional Keywordsdnmt 3a2/3b3, nucleosome, dna methylation, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
Biological sourceHomo sapiens (human)
More
Total number of polymer chains26
Total formula weight1075557.57
Authors
Xie, X.,Liu, M.,Zhou, X.E.,Worden, E.,Jones, P. (deposition date: 2024-10-22, release date: 2026-02-18)
Primary citationXie, X.,Liu, M.,Zhou, X.E.,Worden, E.,Jones, P.
The structural basis for de novo DNA methylation in chromatin
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.14 Å)
Structure validation

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PDB entries from 2026-02-25

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