9E17

Structure of RyR1 in the primed state in the presence of caffeine (reprocessed/reanalyzed from EMPIAR-10997, 7TZC, EMD-26205)

This is a non-PDB format compatible entry.

Summary for 9E17

• Entry DOI: 10.2210/pdb9e17/pdb
• EMDB information: 26205 47357
• Descriptor: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ... (10 entities in total)
• Functional Keywords: calcium channel, transport protein, sarcoplasmic reticulum
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 2392988.18

Authors

Miotto, M.C.,Marks, A.R. (deposition date: 2024-10-21, release date: 2024-10-30)

• Primary citation: Miotto, M.C.; Targeting Ryanodine Receptors with Allopurinol and Xanthine Derivatives for the Treatment of Cardiac and Musculoskeletal Weakness Disorders; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.45 Å)