9DY6

Structure of PmHMGR bound to mevalonate, CoA and NAD 4 minutes after reaction initiation at pH 9

This is a non-PDB format compatible entry.

Summary for 9DY6

• Entry DOI: 10.2210/pdb9dy6/pdb
• Related: 8GDN 8VLQ 9DCP 9DG2 9DPG
• Descriptor: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, Mevaldyl-Coenzyme A, COENZYME A, ... (7 entities in total)
• Functional Keywords: non-rossmann fold, homodimer, reductase, hmg-coa, structural protein, oxidoreductase, oxidoreductase-substrate-intermediate complex, oxidoreductase/substrate/intermediate
• Biological source: Pseudomonas sp. 'mevalonii'
• Total number of polymer chains: 2
• Total formula weight: 93922.42

Authors

Purohit, V.,Steussy, C.N.,Schmidt, T.,Stauffacher, C.V.,Rushton, P. (deposition date: 2024-10-13, release date: 2026-11-04)

• Primary citation: Patel, H.,Purohit, V.,Steussy, C.S.,Stauffacher, C.V.,Helquist, P.,Wiest, O.,Schmidt, T.,Rushton, P.; Watching Pseudomonas mevalonii HMG-CoA Reductase in Action; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)