9DVY

Human mitochondrial ClpX with endogenous substrate

Summary for 9DVY

• Entry DOI: 10.2210/pdb9dvy/pdb
• EMDB information: 47226
• Descriptor: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, Unidentified endogenous substrate, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: mitochondrial protein, aaa+ atpase, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 7
• Total formula weight: 314675.52

Authors

Chen, W.C. (deposition date: 2024-10-08, release date: 2025-10-15, Last modification date: 2026-03-04)

• Primary citation: Chen, W.,Lander, G.C.,Yang, J.; Cryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation; Nat Commun, 17:1064-, 2026; DOI: 10.1038/s41467-025-67010-1

Experimental method

ELECTRON MICROSCOPY (3.2 Å)