9DPG

Structure of PmHMGR bound to mevalonate, CoA and NAD 2 minutes 20 seconds after reaction initiation at pH 9

This is a non-PDB format compatible entry.

Summary for 9DPG

• Entry DOI: 10.2210/pdb9dpg/pdb
• Related: 8VLQ 9DCP 9DG2 9DY6
• Descriptor: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, SULFATE ION, ... (8 entities in total)
• Functional Keywords: non-rossmann fold, homodimer, reductase, hmg-coa, structural protein, oxidoreductase-substrate-intermediate complex, oxidoreductase/substrate/intermediate
• Biological source: Pseudomonas sp. 'mevalonii'
• Total number of polymer chains: 2
• Total formula weight: 94018.49

Authors

Purohit, V.,Steussy, C.N.,Schmidt, T.,Stauffacher, C.V.,Rushton, P. (deposition date: 2024-09-21, release date: 2026-04-08)

• Primary citation: Patel, H.,Purohit, V.,Steussy, C.S.,Stauffacher, C.V.,Helquist, P.,Wiest, O.,Schmidt, T.,Rushton, P.; Watching Pseudomonas mevalonii HMG-CoA Reductase in Action; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.5 Å)