9DN6

Insulin receptor bound with de novo designed agonist called "RF-405".

Summary for 9DN6

• Entry DOI: 10.2210/pdb9dn6/pdb
• EMDB information: 47031
• Descriptor: De novo designed IR agonist RF-405, Isoform Short of Insulin receptor (2 entities in total)
• Functional Keywords: insulin receptor, de novo designed agonist, signaling protein
• Biological source: synthetic construct; More
• Total number of polymer chains: 4
• Total formula weight: 341235.56

Authors

Bai, X.C. (deposition date: 2024-09-16, release date: 2025-10-01)

• Primary citation: Bai, X.C.; Tuning insulin receptor signaling using de novo designed agonists; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4 Å)