9DKP

The structure of human vacuolar protein sorting 34 catalytic domain bound to RD-I-53

This is a non-PDB format compatible entry.

Summary for 9DKP

• Entry DOI: 10.2210/pdb9dkp/pdb
• Descriptor: Phosphatidylinositol 3-kinase catalytic subunit type 3, diethyl ether, DIMETHYL SULFOXIDE, ... (8 entities in total)
• Functional Keywords: phosphatidylinositol 3-phosphate, lipid regulator, autophagy, membrane trafficking, endocytosis, enzyme, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 69296.84

Authors

Abiodun, W.O.,Tsubaki, E.,Dass, R.,Singleton, J.D.,Samarawickrama, P.,Doukov, T.,Peterson, M.A.,Moody, J.D. (deposition date: 2024-09-09, release date: 2025-09-17, Last modification date: 2026-06-24)

• Primary citation: Abiodun, W.O.,Dass, R.,Tsubaki, E.,Singleton, J.D.,Fullmer, A.,Cartwright, J.,Litchfield, C.,Samarawickrama, P.,Doukov, T.,Peterson, M.A.,Moody, J.D.; Facile Bacterial Production of Human Vacuolar Protein Sorting 34 Enables Structural Characterization of Novel Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.16 Å)