9DJ9
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in distinct apo form
Summary for 9DJ9
Entry DOI | 10.2210/pdb9dj9/pdb |
Related | 8TK2 8TK3 8TK4 8TK5 8TK6 |
Descriptor | Dual specificity protein phosphatase 3 (2 entities in total) |
Functional Keywords | phosphatase, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 20984.73 |
Authors | Keedy, D.A.,Lemberikman, A.M.,Isiorho, E.A.,Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2024-09-06, release date: 2024-09-25) |
Primary citation | Wu, J.,Baranowski, M.R.,Aleshin, A.E.,Lambert, L.J.,Isiorho, E.A.,Lemberikman, A.M.,Keedy, D.A.,Cosford, N.D.P.,Tautz, L. Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.924 Å) |
Structure validation
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