9DG2

PmHMGR bound to mevalonate, CoA, and NAD, buffer-exchanged to ammonium acetate environment at pH 6.7

Summary for 9DG2

• Entry DOI: 10.2210/pdb9dg2/pdb
• Related: 8GDN 8VLQ 9DCP 9DPG 9DY6
• Descriptor: 3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, (R)-MEVALONATE, ... (6 entities in total)
• Functional Keywords: non-rossmann fold, homodimer, reductase, hmg-coa, structural protein, oxidoreductase
• Biological source: Pseudomonas sp. 'mevalonii'
• Total number of polymer chains: 2
• Total formula weight: 93103.80

Authors

Purohit, V.,Steussy, C.N.,Schmidt, T.,Stauffacher, C.V.,Rushton, P. (deposition date: 2024-09-01, release date: 2026-03-18)

• Primary citation: Patel, H.,Purohit, V.,Steussy, C.S.,Stauffacher, C.V.,Helquist, P.,Wiest, O.,Schmidt, T.,Rushton, P.; Watching Pseudomonas mevalonii HMG-CoA Reductase in Action; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.93 Å)