9DDB

Cryo-EM structure of gB-Ecto.516P.531E, a prefusion-stabilized HSV-1 glycoprotein B extracellular domain

Summary for 9DDB

• Entry DOI: 10.2210/pdb9ddb/pdb
• EMDB information: 46763
• Descriptor: Glycoprotein B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: gb trimer, fusogen, postfusion-destabilization, viral protein
• Biological source: Human alphaherpesvirus 1 (Herpes simplex virus type 1)
• Total number of polymer chains: 3
• Total formula weight: 275320.38

Authors

Roark, R.S.,Shapiro, L.,Kwong, P.D. (deposition date: 2024-08-27, release date: 2025-09-10)

• Primary citation: Roark, R.S.,Shapiro, L.,Kwong, P.D.; Herpes simplex virus 1 evades prefusion gB neutralization; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.71 Å)