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9DCP

Structure of PmHMGR bound to mevalonate, CoA and NAD 1 minute after reaction initiation at pH 9

This is a non-PDB format compatible entry.
Summary for 9DCP
Entry DOI10.2210/pdb9dcp/pdb
Related8GDN 8VLQ 9DG2 9DPG 9DY6
Descriptor3-hydroxy-3-methylglutaryl-coenzyme A reductase, COENZYME A, (R)-mevaldehyde, ... (7 entities in total)
Functional Keywordscomplex, reaction intermediate, enzyme, oxidoreductase, oxidoreductase-substrate-intermediate complex, oxidoreductase/substrate/intermediate
Biological sourcePseudomonas sp. 'mevalonii'
Total number of polymer chains2
Total formula weight94439.71
Authors
Purohit, V.,Stauffacher, C.V. (deposition date: 2024-08-27, release date: 2026-03-18)
Primary citationPatel, H.,Purohit, V.,Steussy, C.S.,Stauffacher, C.V.,Helquist, P.,Wiest, O.,Schmidt, T.,Rushton, P.
Watching Pseudomonas mevalonii HMG-CoA Reductase in Action
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.06 Å)
Structure validation

251174

PDB entries from 2026-03-25

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