9D8T

Crystal structure of KPC-2 complexed with compound 16

This is a non-PDB format compatible entry.

Summary for 9D8T

• Entry DOI: 10.2210/pdb9d8t/pdb
• Related: 9D2U 9D54 9D5Q 9D5R
• Descriptor: Carbapenem-hydrolyzing beta-lactamase KPC, SULFATE ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: inhibitor, beta-lactamase, complex, kpc, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 31491.06

Authors

Jacobs, L.M.C.,Chen, Y. (deposition date: 2024-08-20, release date: 2025-09-03)

• Primary citation: Jacobs, L.M.C.,Chen, Y.,Renslo, A.; Hit to Lead Optimization of Heteroaryl Phosphonates Reversible, Broad-Spectrum Inhibitors of Serine and Metallo Carbapenemases.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)