9D2U

Crystal structure of KPC-2 complexed with compound 14

This is a non-PDB format compatible entry.

Summary for 9D2U

• Entry DOI: 10.2210/pdb9d2u/pdb
• Related: 9D54 9D5Q 9D5R 9D8T 9D9N 9DAG 9DB7 9DE3 9DEW
• Descriptor: Carbapenem-hydrolyzing beta-lactamase KPC, {[6-fluoro-1-methyl-7-(morpholin-4-yl)-2-oxo-1,2-dihydroquinolin-4-yl]methyl}phosphonic acid, SULFATE ION, ... (5 entities in total)
• Functional Keywords: inhibitor, beta-lactamase, complex, kpc, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 31639.26

Authors

Jacobs, L.M.C.,Chen, Y. (deposition date: 2024-08-09, release date: 2025-10-29)

• Primary citation: Jacobs, L.M.C.,Chen, Y.,Renslo, A.; Hit to Lead Optimization of Heteroaryl Phosphonates Reversible, Broad-Spectrum Inhibitors of Serine and Metallo Carbapenemases.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)