9D8G

Human p38alpha MAP Kinase in complex with (Naphthalen-2-yl)pyridazine derivative; KES29

This is a non-PDB format compatible entry.

Summary for 9D8G

• Entry DOI: 10.2210/pdb9d8g/pdb
• Descriptor: Mitogen-activated protein kinase 14, 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, N',N'-dimethyl-N-(6-naphthalen-2-yl-5-pyridin-4-yl-pyridazin-3-yl)ethane-1,2-diamine, ... (4 entities in total)
• Functional Keywords: p38, kinase, inhibitor, complex, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 42191.15

Authors

Brunzelle, J.S.,Shuvalova, L.,Knez, D.,Meden, A.,Roy, S.M.,Watterson, D.M.,Gobec, S. (deposition date: 2024-08-19, release date: 2026-02-11)

• Primary citation: Brunzelle, J.S.,Shuvalova, L.,Knez, D.,Meden, A.,Roy, S.M.,Watterson, D.M.,Gobec, S.; Human p38alpha MAP Kinase in complex with (Naphthalen-2-yl)pyridazine derivative; KES29; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.13 Å)