9D62

Crystal structure of Human Galectin-3 CRD in complex with Lactose (native)

Summary for 9D62

Entry DOI	10.2210/pdb9d62/pdb
Descriptor	Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywords	galectin-3, lactose, c-terminal, crd, sugar binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	16906.10
Authors	dos Santos, L.V.,Dias, I.P.,Mazepa, E.,Minella, T.F.,Baruffi, M.R.,Mestriner, L.,Nascimento, A.F.Z.,Albuquerque, L.J.C.,Mischiatti, K.L.,Winnischofer, S.M.B.,Amaral, S.S.,Silveira, J.L.M.,Picheth, G.F. (deposition date: 2024-08-14, release date: 2026-03-18)
Primary citation	dos Santos, L.V.,Dias, I.P.,Mazepa, E.,Minella, T.F.,Baruffi, M.R.,Mestriner, L.,Nascimento, A.F.Z.,Albuquerque, L.J.C.,Mischiatti, K.L.,Winnischofer, S.M.B.,Amaral, S.S.,Silveira, J.L.M.,Picheth, G.F. Exploring the interactive effect of pectins with galectin-3 to reduce the viability of T98G glioblastoma cell lineage To Be Published,
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation