9CXA

Native human GABAA receptor of beta2-alpha1-beta3-alpha1-gamma2 assembly

This is a non-PDB format compatible entry.

Summary for 9CXA

• Entry DOI: 10.2210/pdb9cxa/pdb
• EMDB information: 45983
• Descriptor: Gamma-aminobutyric acid receptor subunit beta-2, GAMMA-AMINO-BUTANOIC ACID, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ... (13 entities in total)
• Functional Keywords: native, gabaa, ligand gated ion channel, neurotransmitter receptor, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 9
• Total formula weight: 436181.80

Authors

Zhou, J.,Hibbs, R.E.,Noviello, C.M. (deposition date: 2024-07-31, release date: 2025-01-22)

• Primary citation: Zhou, J.,Noviello, C.M.,Teng, J.,Moore, H.,Lega, B.,Hibbs, R.E.; Resolving native GABAA receptor structures from the human brain; Nature, 2025; DOI: 10.1038/s41586-024-08454-1

Experimental method

ELECTRON MICROSCOPY (3.04 Å)