9CTS

Best1 + GABA intermediate state 2

Summary for 9CTS

• Entry DOI: 10.2210/pdb9cts/pdb
• EMDB information: 45917
• Descriptor: Bestrophin-1, CALCIUM ION, GAMMA-AMINO-BUTANOIC ACID (3 entities in total)
• Functional Keywords: calcium-activated chloride channel, gaba type a receptor, gaba-bound anion channel, channel-activator complex, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 5
• Total formula weight: 338759.23

Authors

Owji, A.P.,Kittredge, A.,Zhang, Y.,Yang, T. (deposition date: 2024-07-25, release date: 2024-09-25)

• Primary citation: Wang, J.,Owji, A.P.,Kittredge, A.,Clark, Z.,Zhang, Y.,Yang, T.; GAD65 tunes the functions of Best1 as a GABA receptor and a neurotransmitter conducting channel.; Nat Commun, 15:8051-8051, 2024; PubMed: 39277606; DOI: 10.1038/s41467-024-52039-5

Experimental method

ELECTRON MICROSCOPY (2.45 Å)