9CS1

E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP2

Summary for 9CS1

• Entry DOI: 10.2210/pdb9cs1/pdb
• Related PRD ID: PRD_002330
• Descriptor: Outer membrane protein assembly factor BamA, Cyclic peptide CP2, Darobactin A, ... (5 entities in total)
• Functional Keywords: beta barrel, outer membrane protein, membrane protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 3
• Total formula weight: 46849.59

Authors

Walker, M.E.,Gu, M.,Lu, J.,Klein, D.J. (deposition date: 2024-07-23, release date: 2025-04-16)

• Primary citation: Walker, M.E.,Zhu, W.,Peterson, J.H.,Wang, H.,Patteson, J.,Soriano, A.,Zhang, H.,Mayhood, T.,Hou, Y.,Mesbahi-Vasey, S.,Gu, M.,Frost, J.,Lu, J.,Johnston, J.,Hipolito, C.,Lin, S.,Painter, R.E.,Klein, D.,Walji, A.,Weinglass, A.,Kelly, T.M.,Saldanha, A.,Schubert, J.,Bernstein, H.D.,Walker, S.S.; Antibacterial macrocyclic peptides reveal a distinct mode of BamA inhibition; Nat Commun, 16:3395-, 2025; DOI: 10.1038/s41467-025-58086-w

Experimental method

X-RAY DIFFRACTION (2.147 Å)