9CMM

Two protofilament structure of alpha1B and betaI/IVb microtubule bound to GMPCPP

Summary for 9CMM

• Entry DOI: 10.2210/pdb9cmm/pdb
• Related: 8V2J 9BP6 9COC 9CRR
• EMDB information: 45750 45775 45877
• Descriptor: Tubulin beta chain, Tubulin alpha-1B chain, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... (5 entities in total)
• Functional Keywords: human microtubule, tubulin isoforms, cytoskeleton, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 404060.29

Authors

Zehr, E.A.,Roll-Mecak, A. (deposition date: 2024-07-15, release date: 2026-03-18)

• Primary citation: Zehr, E.A.,Roll-Mecak, A.; Cryo-EM structures of human a1B/bI+bIVb microtubules shed light on isoform specific assembly; bioRxiv, 2023; DOI: 10.1101/2023.12.01.569594

Experimental method

ELECTRON MICROSCOPY (3.1 Å)