9CKO

Human G protein-coupled receptor kinase 5 wild-type in complex with sangivamycin

9CKO の概要

• エントリーDOI: 10.2210/pdb9cko/pdb
• 分子名称: G protein-coupled receptor kinase 5, ACETYL GROUP, SANGIVAMYCIN, ... (5 entities in total)
• 機能のキーワード: gpcr, grk, g protein-coupled receptor, g protein-coupled receptor kinase, gpcr signaling, signaling protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 69325.14

構造登録者

Chen, Y.,Tesmer, J.J.G. (登録日: 2024-07-09, 公開日: 2025-07-16)

• 主引用文献: Chen, Y.,Tesmer, J.J.G.; Structures of G protein-coupled receptor kinase 5 in multiple conformations reveals mechanism of activation and inhibition; To Be Published,

実験手法

X-RAY DIFFRACTION (2.8 Å)