9CGQ

Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6, nanodisc and inhibitor dantrolene in the presence of activating calcium

This is a non-PDB format compatible entry.

Summary for 9CGQ

• Entry DOI: 10.2210/pdb9cgq/pdb
• Related: 7T64 7T65 9CGP
• EMDB information: 45493 45585
• Descriptor: Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... (6 entities in total)
• Functional Keywords: ryanodine receptor, calcium channel, mutation, y523s, ryr1, dantrolene, membrane protein
• Biological source: Oryctolagus cuniculus (rabbit); More
• Total number of polymer chains: 8
• Total formula weight: 2313707.15

Authors

Iyer, K.A.,Samso, M. (deposition date: 2024-06-30, release date: 2024-12-11)

• Primary citation: Iyer, K.A.,Kobayashi, T.,Murayama, T.,Samso, M.; Manuscript in preparation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.23 Å)