9CG4

Cryo-EM structure of FAN1, PCNA and DNA substrate with (CAG)2 extrusion in intermediate state

Summary for 9CG4

• Entry DOI: 10.2210/pdb9cg4/pdb
• EMDB information: 45568
• Descriptor: Proliferating cell nuclear antigen, Fanconi-associated nuclease 1, DNA (5'-D(P*CP*GP*AP*AP*TP*TP*TP*CP*TP*AP*GP*AP*CP*TP*CP*GP*AP*GP*AP*TP*CP*AP*G)-3'), ... (4 entities in total)
• Functional Keywords: nuclease, cag expansion, dna repair, huntington's disease, dna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 120438.27

Authors

Fenglin, L.,Anna, P. (deposition date: 2024-06-28, release date: 2025-02-19)

• Primary citation: Fenglin, L.,Anna, P.; cryo-EM structure of FAN1-PCNA-DNA complex in intermediate state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.37 Å)