9CG4
Cryo-EM structure of FAN1, PCNA and DNA substrate with (CAG)2 extrusion in intermediate state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, C, D) | Proliferating cell nuclear antigen | polymer | 261 | 28795.8 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens (human) | PCNA,Cyclin |
| 2 | D (E) | Fanconi-associated nuclease 1 | polymer | 183 | 20853.4 | 1 | UniProt (Q9Y2M0) Pfam (PF21315) Pfam (PF21169) | Homo sapiens (human) | FANCD2/FANCI-associated nuclease 1,hFAN1,Myotubularin-related protein 15 |
| 3 | E (A) | DNA (5'-D(P*CP*GP*AP*AP*TP*TP*TP*CP*TP*AP*GP*AP*CP*TP*CP*GP*AP*GP*AP*TP*CP*AP*G)-3') | polymer | 23 | 7064.6 | 1 | synthetic construct | ||
| 4 | F (F) | DNA (5'-D(P*AP*TP*CP*TP*CP*GP*AP*GP*TP*CP*TP*AP*GP*AP*AP*AP*TP*TP*CP*G)-3') | polymer | 20 | 6133.0 | 1 | synthetic construct |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 120438.3 | |
| All* | Total formula weight | 120438.3 |
