9CDS

Crystal structure of OspA ST1 from B. burgdorferi bound to monoclonal antibody LA-2

Summary for 9CDS

• Entry DOI: 10.2210/pdb9cds/pdb
• Descriptor: Hybridoma Antibody LA2 (Light Chain), Hybridoma Antibody LA2 (Heavy Chain), Outer surface protein A, ... (4 entities in total)
• Functional Keywords: lyme disease, outer surface protein a (ospa), immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 155740.28

Authors

Laciak, A.R.,Lai, Y.-T.,Dhingra, Y. (deposition date: 2024-06-25, release date: 2025-09-24)

• Primary citation: Finn, M.B.,Dold, C.,Willsey, G.,Piazza, C.L.,Clendenen, L.,Shrestha, M.,You, S.S.,Ma, L.,Dhingra, Y.,Laciak, A.R.,Uggowitzer, K.A.,Obiero, J.M.,Natarajan, H.,Green, S.,Pirayesh, E.,Lai, Y.-T.,Himansu, S.,Carfi, A.,Hu, L.T.,Mantis, N.,Plante, O.; Preclinical assessment of an investigational mRNA lipid nanoparticle OspA vaccine for Lyme disease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)