9CBS
Crystal structure of Chaetomium thermophilum Gcn2 HisRS-like domain, catalytic domain
Summary for 9CBS
Entry DOI | 10.2210/pdb9cbs/pdb |
Related | 9C9Q 9C9R |
Descriptor | non-specific serine/threonine protein kinase (2 entities in total) |
Functional Keywords | stress response, gcn2, trna-binding, regulatory, translation |
Biological source | Thermochaetoides thermophila |
Total number of polymer chains | 4 |
Total formula weight | 150431.83 |
Authors | Zhang, J. (deposition date: 2024-06-20, release date: 2024-08-21, Last modification date: 2024-09-18) |
Primary citation | Bou-Nader, C.,Gaikwad, S.,Bahmanjah, S.,Zhang, F.,Hinnebusch, A.G.,Zhang, J. Gcn2 structurally mimics and functionally repurposes the HisRS enzyme for the integrated stress response. Proc.Natl.Acad.Sci.USA, 121:e2409628121-e2409628121, 2024 Cited by PubMed: 39163341DOI: 10.1073/pnas.2409628121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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