9CBK

Crystal Structure of Danio rerio Histone Deacetylase 6 in Complex with p-Aminomethyl Phenylthioketone

This is a non-PDB format compatible entry.

Summary for 9CBK

• Entry DOI: 10.2210/pdb9cbk/pdb
• Descriptor: Hdac6 protein, 1-[4-(aminomethyl)phenyl]-2-sulfanylethan-1-one, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: hydrolase, histone deacetylase, inhibitor, metallohydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Danio rerio (zebrafish)
• Total number of polymer chains: 2
• Total formula weight: 81468.96

Authors

Goulart Stollmaier, J.,Watson, P.R.,Christianson, D.W. (deposition date: 2024-06-19, release date: 2024-09-11)

• Primary citation: Goulart Stollmaier, J.,Watson, P.R.,Christianson, D.W.; Design, Synthesis, and Structural Evaluation of Acetylated Phenylthioketone Inhibitors of HDAC10; To be Published,

Experimental method

X-RAY DIFFRACTION (1.46 Å)