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9C7E

Diheteromeric GluN1/GluN2A (delM653) in nanodisc complex with glycine, glutamate, and GNE-4123, open conformation, C2 symmetry

This is a non-PDB format compatible entry.
Summary for 9C7E
Entry DOI10.2210/pdb9c7e/pdb
EMDB information45279
DescriptorGlutamate receptor ionotropic, NMDA 1,Green fluorescent protein chimera, Glutamate receptor ionotropic, NMDA 2A,Green fluorescent protein chimera, 4-cyclohexyl-N-[(8R)-2-cyclopropyl-7-hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]benzene-1-sulfonamide, ... (5 entities in total)
Functional Keywordsion channel, nmda, positive allosteric modulator, open pore conformation, transport protein
Biological sourceRattus norvegicus (Norway rat)
More
Total number of polymer chains4
Total formula weight506346.86
Authors
Jalali-Yazdi, F.,Kim, J.,Gouaux, E. (deposition date: 2024-06-10, release date: 2025-09-24)
Primary citationJalali-Yazdi, F.,Kim, J.,Gouaux, E.
Diheteromeric GluN1/GluN2A (delM653) in nanodisc complexed with glycine, glutamate, and GNE-4123, open-pore conformation, processed in C2 symmetry
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.22 Å)
Structure validation

242842

数据于2025-10-08公开中

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