9C66

Structure of the Mena EVH1 domain bound to the polyproline segment of PTP1B

Summary for 9C66

• Entry DOI: 10.2210/pdb9c66/pdb
• Descriptor: Protein enabled homolog, poly-proline segment of PTP1B, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: mena, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 14223.04

Authors

LaComb, L.,Fedorov, E.,Bonanno, J.B.,Almo, S.C.,Ghosh, A. (deposition date: 2024-06-07, release date: 2024-08-28, Last modification date: 2024-09-11)

• Primary citation: LaComb, L.,Ghosh, A.,Bonanno, J.B.,Nilson, D.J.,Poppel, A.J.,Dada, L.,Cahill, S.M.,Maianti, J.P.,Kitamura, S.,Cowburn, D.,Almo, S.C.; Insights into the Interaction Landscape of the EVH1 Domain of Mena.; Biochemistry, 63:2183-2195, 2024; PubMed: 39138154; DOI: 10.1021/acs.biochem.4c00331

Experimental method

X-RAY DIFFRACTION (1.4 Å)