9C5K

Trypanosoma cruzi R19T/K20S/C64Y mutant beta-3-HBDH structure in complex with NADPH and malonate

Summary for 9C5K

• Entry DOI: 10.2210/pdb9c5k/pdb
• Descriptor: Hydroxybutyrate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: trypanosoma cruzi, nadph, malonate, beta-3-hydroxybutyrate dehydrogenase, oxidoreductase
• Biological source: Trypanosoma cruzi
• Total number of polymer chains: 4
• Total formula weight: 118995.28

Authors

Hashimoto, H.,Debler, E.W. (deposition date: 2024-06-06, release date: 2025-08-27)

• Primary citation: Hashimoto, H.,Debler, E.W.; Trypanosoma cruzi D-3-hydroxybutyrate dehydrogenase (HBDH) is NADP-dependent enzyme.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.79 Å)