9C1P
Structure of Calcium-Sensing Receptor in complex with positive allosteric modulator '6218
This is a non-PDB format compatible entry.
Summary for 9C1P
Entry DOI | 10.2210/pdb9c1p/pdb |
EMDB information | 45127 |
Descriptor | Extracellular calcium-sensing receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | g-protein coupled receptor, calcium-sensing, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 216883.07 |
Authors | |
Primary citation | Liu, F.,Wu, C.G.,Tu, C.L.,Glenn, I.,Meyerowitz, J.,Kaplan, A.L.,Lyu, J.,Cheng, Z.,Tarkhanova, O.O.,Moroz, Y.S.,Irwin, J.J.,Chang, W.,Shoichet, B.K.,Skiniotis, G. Large library docking identifies positive allosteric modulators of the calcium-sensing receptor. Science, 385:eado1868-eado1868, 2024 Cited by PubMed: 39298584DOI: 10.1126/science.ado1868 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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