9BYO

Cryo-EM structure of glucagon-like peptide-1 receptor (GLP-1R)-Gs complex with Exendin-asp3

Summary for 9BYO

• Entry DOI: 10.2210/pdb9byo/pdb
• EMDB information: 45040
• Descriptor: Glucagon-like peptide 1 receptor, Exendin-3, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (7 entities in total)
• Functional Keywords: cryo-em glucagon-like peptide-1 receptor exendin-asp3 biased agonist, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 164284.05

Authors

Zhang, X.,Johnson, R.,Belousoff, M.J.,Danev, R.,Sexton, P.M.,Wootten, D. (deposition date: 2024-05-24, release date: 2025-06-11)

• Primary citation: Zhang, X.,Belousoff, M.J.,Danev, R.,Sexton, P.M.,Wootten, D.; Structural insights in the activation of GLP-1R by biased ligands; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.31 Å)