9BS4
DNA Ligase 1 E346A/E592A double mutant with 5'-rG:C
Summary for 9BS4
Entry DOI | 10.2210/pdb9bs4/pdb |
Descriptor | DNA ligase 1, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*G)-3'), DNA/RNA (5'-R(P*G)-D(P*TP*CP*GP*GP*AP*C)-3'), ... (6 entities in total) |
Functional Keywords | dna binding protein, dna repair, ber, human dna ligase 1, ligase, ligase-dna complex, ligase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 165870.64 |
Authors | KanalElamparithi, B.,Caglayan, M. (deposition date: 2024-05-12, release date: 2024-09-25, Last modification date: 2024-10-16) |
Primary citation | Balu, K.E.,Tang, Q.,Almohdar, D.,Ratcliffe, J.,Kalaycioglu, M.,Caglayan, M. Structures of LIG1 uncover the mechanism of sugar discrimination against 5'-RNA-DNA junctions during ribonucleotide excision repair. J.Biol.Chem., 300:107688-107688, 2024 Cited by PubMed: 39159820DOI: 10.1016/j.jbc.2024.107688 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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