9BR1

Structure of the SARS-CoV-2 main protease in complex with inhibitor VB-A-70

This is a non-PDB format compatible entry.

Summary for 9BR1

• Entry DOI: 10.2210/pdb9br1/pdb
• Descriptor: 3C-like proteinase nsp5, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-{(1S,2R)-1-(1,3-benzoxazol-2-yl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-3-cyclohexyl-L-alaninamide (3 entities in total)
• Functional Keywords: main protease, viral protein, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34545.41

Authors

Blankenship, L.R.,Liu, W.R. (deposition date: 2024-05-10, release date: 2025-05-14)

• Primary citation: Blankenship, L.R.,Liu, W.R.; Structure of the SARS-CoV-2 main protease; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)