9BQF

Structure of the SARS-CoV-2 main protease in complex with inhibitor 78

Summary for 9BQF

• Entry DOI: 10.2210/pdb9bqf/pdb
• Descriptor: 3C-like proteinase nsp5, N-[(BENZYLOXY)CARBONYL]-O-(TERT-BUTYL)-L-THREONYL-3-CYCLOHEXYL-N-[(1S)-2-HYDROXY-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}ETHYL]-L-ALANINAMIDE (2 entities in total)
• Functional Keywords: main protease, viral protein, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 34428.31

Authors

Blankenship, L.R.,Liu, W.R. (deposition date: 2024-05-09, release date: 2025-05-14)

• Primary citation: Blankenship, L.R.,Liu, W.R.; Structure of the SARS-CoV-2 main protease in complex with inhibitor 78; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)