9BL0

KRAS G12D Mutant KRAS 1-169 at 298 K bound to MRTX-1133

Summary for 9BL0

• Entry DOI: 10.2210/pdb9bl0/pdb
• Descriptor: Isoform 2B of GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: gtpase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 40751.64

Authors

Xu, M.,Deck, S.L.,Milano, S.K.,Aplin, C.,Cerione, R.A. (deposition date: 2024-04-29, release date: 2025-05-07)

• Primary citation: Xu, M.,Deck, S.L.,Milano, S.K.,Aplin, C.,Cerione, R.A.; Room Temperature Structures of Oncogenic KRAS-G12D bound to MRTX-1133; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.66 Å)