9BJK

Inactive mu opioid receptor bound to Nb6, naloxone and NAM

This is a non-PDB format compatible entry.

Summary for 9BJK

• Entry DOI: 10.2210/pdb9bjk/pdb
• EMDB information: 44635
• Descriptor: kappa opioid receptor Nanobody 6, Mu-type opioid receptor, Naloxone, ... (4 entities in total)
• Functional Keywords: g-protein coupled receptor, inactive, opioid, allosteric modulator, membrane protein
• Biological source: Lama glama; More
• Total number of polymer chains: 2
• Total formula weight: 63584.11

Authors

O'Brien, E.S.,Wang, H.,Kaavya Krishna, K.,Zhang, C.,Kobilka, B.K. (deposition date: 2024-04-25, release date: 2024-07-17)

• Primary citation: O'Brien, E.S.,Rangari, V.A.,El Daibani, A.,Eans, S.O.,Hammond, H.R.,White, E.,Wang, H.,Shiimura, Y.,Krishna Kumar, K.,Jiang, Q.,Appourchaux, K.,Huang, W.,Zhang, C.,Kennedy, B.J.,Mathiesen, J.M.,Che, T.,McLaughlin, J.P.,Majumdar, S.,Kobilka, B.K.; A mu-opioid receptor modulator that works cooperatively with naloxone.; Nature, 2024; PubMed: 38961287; DOI: 10.1038/s41586-024-07587-7

Experimental method

ELECTRON MICROSCOPY (3.26 Å)