9BJK
Inactive mu opioid receptor bound to Nb6, naloxone and NAM
This is a non-PDB format compatible entry.
Summary for 9BJK
Entry DOI | 10.2210/pdb9bjk/pdb |
EMDB information | 44635 |
Descriptor | kappa opioid receptor Nanobody 6, Mu-type opioid receptor, Naloxone, ... (4 entities in total) |
Functional Keywords | g-protein coupled receptor, inactive, opioid, allosteric modulator, membrane protein |
Biological source | Lama glama More |
Total number of polymer chains | 2 |
Total formula weight | 63584.11 |
Authors | O'Brien, E.S.,Wang, H.,Kaavya Krishna, K.,Zhang, C.,Kobilka, B.K. (deposition date: 2024-04-25, release date: 2024-07-17, Last modification date: 2024-08-14) |
Primary citation | O'Brien, E.S.,Rangari, V.A.,El Daibani, A.,Eans, S.O.,Hammond, H.R.,White, E.,Wang, H.,Shiimura, Y.,Krishna Kumar, K.,Jiang, Q.,Appourchaux, K.,Huang, W.,Zhang, C.,Kennedy, B.J.,Mathiesen, J.M.,Che, T.,McLaughlin, J.P.,Majumdar, S.,Kobilka, B.K. A mu-opioid receptor modulator that works cooperatively with naloxone. Nature, 631:686-693, 2024 Cited by PubMed: 38961287DOI: 10.1038/s41586-024-07587-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.26 Å) |
Structure validation
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