9BGE

Cryo-EM structure of mAb8-24 bound to 426c.WITO.TM.SOSIP

Summary for 9BGE

• Entry DOI: 10.2210/pdb9bge/pdb
• Related: 9B44
• EMDB information: 44510
• Descriptor: 426c.WITO.TM.SOSIP, Fv domain of heavy chain of mAb 8-24, Fv domain of light chain of mAb 8-24, ... (8 entities in total)
• Functional Keywords: hiv, antibody, immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 9
• Total formula weight: 376896.79

Authors

Hurlburt, N.K.,Pancera, M. (deposition date: 2024-04-18, release date: 2024-09-04, Last modification date: 2024-09-18)

• Primary citation: Agrawal, P.,Knudsen, M.L.,MacCamy, A.,Hurlburt, N.K.,Khechaduri, A.,Salladay, K.R.,Kher, G.M.,Kallur Siddaramaiah, L.,Stuart, A.B.,Bontjer, I.,Shen, X.,Montefiori, D.,Gristick, H.B.,Bjorkman, P.J.,Sanders, R.W.,Pancera, M.,Stamatatos, L.; Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env.; J.Virol., :e0074424-e0074424, 2024; PubMed: 39240111; DOI: 10.1128/jvi.00744-24

Experimental method

ELECTRON MICROSCOPY (4.2 Å)