9BFD

Tyrocidine synthetase modules 1 and 2 crosslinked in the condensation state, complex A

This is a non-PDB format compatible entry.

Summary for 9BFD

• Entry DOI: 10.2210/pdb9bfd/pdb
• EMDB information: 44493
• Descriptor: Tyrocidine synthase 1, Tyrocidine synthase 2, (7S,10aR)-1-methyl-4-{4-[(5R)-1,1,5-trihydroxy-4,4-dimethyl-1,6,11-trioxo-2-oxa-7,10-diaza-1lambda~5~-phosphadodecan-12-yl]phenyl}-3,5,6,7,8,9,10,10a-octahydrocycloocta[d]pyridazin-7-yl [2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]carbamate, ... (4 entities in total)
• Functional Keywords: complex, crosslinked, nrps, isomerase
• Biological source: Brevibacillus parabrevis; More
• Total number of polymer chains: 2
• Total formula weight: 245231.12

Authors

Heberlig, G.W.,Burkart, M.D. (deposition date: 2024-04-17, release date: 2024-10-09, Last modification date: 2024-10-30)

• Primary citation: Heberlig, G.W.,La Clair, J.J.,Burkart, M.D.; Crosslinking Reveals the Molecular Details of Intermodular Condensation and Epimerization in Nonribosomal Peptide Biosynthesis; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.97 Å)