Summary for 9BD2
Entry DOI | 10.2210/pdb9bd2/pdb |
Descriptor | Melanoma-associated antigen 3, (furan-2-yl)[4-({(5P)-5-(1H-indazol-4-yl)-2-[3-(morpholin-4-yl)propoxy]phenyl}methyl)piperazin-1-yl]methanone (3 entities in total) |
Functional Keywords | mage-a3, melanoma-associated antigen 3, mage, mage-a3 mhd, kl861, oncoprotein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 3 |
Total formula weight | 71555.96 |
Authors | Butrin, A.,Krone, M.W.,Li, K.,Bond, M.J.,Linhares, B.M.,Crews, C. (deposition date: 2024-04-10, release date: 2024-09-18, Last modification date: 2024-09-25) |
Primary citation | Li, K.,Krone, M.W.,Butrin, A.,Bond, M.J.,Linhares, B.M.,Crews, C.M. Development of Ligands and Degraders Targeting MAGE-A3. J.Am.Chem.Soc., 146:24884-24891, 2024 Cited by PubMed: 39190582DOI: 10.1021/jacs.4c05393 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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