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9B7Q

Fab2-7 in complex with the capsid of Adeno-associated virus type 9

This is a non-PDB format compatible entry.
Summary for 9B7Q
Entry DOI10.2210/pdb9b7q/pdb
EMDB information44320
DescriptorCapsid protein VP1, Fab2-7 heavy chain, Fab2-7 light chain (3 entities in total)
Functional Keywordsadeno-associated virus, aav, capsid, fab-complex, antibody, nab, virus
Biological sourceAdeno-associated virus
More
Total number of polymer chains15
Total formula weight428447.85
Authors
Mietzsch, M.,McKenna, R. (deposition date: 2024-03-27, release date: 2025-04-16, Last modification date: 2025-05-14)
Primary citationMietzsch, M.,Nelson, A.R.,Hsi, J.,Zachary, J.,Potts, L.,Chipman, P.,Ghanem, M.,Alexander, I.E.,Logan, G.J.,Huiskonen, J.,McKenna, R.
Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing
Nat Commun, 2025
Experimental method
ELECTRON MICROSCOPY (2.18 Å)
Structure validation

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PDB entries from 2025-05-21

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