9B7P

Fab2-6 in complex with the capsid of Adeno-associated virus type 9

Summary for 9B7P

• Entry DOI: 10.2210/pdb9b7p/pdb
• EMDB information: 44319
• Descriptor: Capsid protein VP1, Fab2-6 light chain, Fab2-6 heavy chain (3 entities in total)
• Functional Keywords: adeno-associated virus, aav, capsid, fab-complex, antibody, nab, virus, viral protein-immune system complex, viral protein/immune system
• Biological source: Adeno-associated virus; More
• Total number of polymer chains: 8
• Total formula weight: 384234.83

Authors

Mietzsch, M.,McKenna, R. (deposition date: 2024-03-27, release date: 2025-04-16, Last modification date: 2025-05-28)

• Primary citation: Mietzsch, M.,Nelson, A.R.,Hsi, J.,Zachary, J.,Potts, L.,Chipman, P.,Ghanem, M.,Alexander, I.E.,Logan, G.J.,Huiskonen, J.,McKenna, R.; Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing; Nat Commun, 2025

Experimental method

ELECTRON MICROSCOPY (2.98 Å)