9B0E

Cryo-EM Structure of E.coli produced recombinant N-acetyltransferase 10 (NAT10) in complex with cytidine-amide-CoA bisubstrate probe and ADP

This is a non-PDB format compatible entry.

Summary for 9B0E

• Entry DOI: 10.2210/pdb9b0e/pdb
• EMDB information: 44038
• Descriptor: RNA cytidine acetyltransferase, ADENOSINE-5'-DIPHOSPHATE, [[(2~{R},3~{S},4~{S},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[2-[[1-[(2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]-2-oxidanylidene-pyrimidin-4-yl]amino]-2-oxidanylidene-ethyl]sulfanylethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate (3 entities in total)
• Functional Keywords: rna binding protein, ac4c modification, rna acetyltransferase
• Biological source: Thermochaetoides thermophila DSM 1495
• Total number of polymer chains: 2
• Total formula weight: 245907.77

Authors

Zhou, M.,Marmorstein, R. (deposition date: 2024-03-12, release date: 2024-09-11)

• Primary citation: Zhou, M.,Gamage, S.T.,Tran, K.A.,Bartee, D.,Wei, X.,Yin, B.,Berger, S.,Meier, J.L.,Marmorstein, R.; Molecular Basis for RNA Cytidine Acetylation by NAT10.; Biorxiv, 2024; PubMed: 38585770; DOI: 10.1101/2024.03.27.587050

Experimental method

ELECTRON MICROSCOPY (3.19 Å)