9AY9

Co-crystal structure of human PRMT9 in complex with MRK-990 inhibitor

これはPDB形式変換不可エントリーです。

9AY9 の概要

• エントリーDOI: 10.2210/pdb9ay9/pdb
• 分子名称: Protein arginine N-methyltransferase 9, 7-[5-S-(4-{[(2-tert-butylpyridin-3-yl)methyl]amino}butyl)-5-thio-beta-D-ribofuranosyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, UNKNOWN ATOM OR ION, ... (4 entities in total)
• 機能のキーワード: methyltransferase, prmt9, sgc, transport protein, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 324003.92

構造登録者

Zeng, H.,Dong, A.,Li, Y.,Hutchinson, A.,Seitova, A.,Li, Y.,Gao, Y.D.,Schneider, S.,Siliphaivanh, P.,Sloman, D.,Nicholson, B.,Fischer, C.,Hicks, J.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (登録日: 2024-03-07, 公開日: 2024-12-04)

• 主引用文献: Zeng, H.,Dong, A.,Li, Y.,Hutchinson, A.,Seitova, A.,Li, Y.,Gao, Y.D.,Schneider, S.,Siliphaivanh, P.,Sloman, D.,Nicholson, B.,Fischer, C.,Hicks, J.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC); Co-crystal structure of human PRMT9 in complex with MRK-990 inhibitor; To be published,

実験手法

X-RAY DIFFRACTION (2.22 Å)