9AXZ

geranine G-induced 2N4R tau filaments

This is a non-PDB format compatible entry.

Summary for 9AXZ

• Entry DOI: 10.2210/pdb9axz/pdb
• EMDB information: 43977
• Descriptor: Isoform Tau-F of Microtubule-associated protein tau, 4-hydroxy-3-{(E)-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]diazenyl}naphthalene-2,7-disulfonic acid (2 entities in total)
• Functional Keywords: microtubule, amyloid, tauopathy, protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 6
• Total formula weight: 277186.04

Authors

Malyshka, D.,Kuret, J. (deposition date: 2024-03-06, release date: 2025-09-10)

• Primary citation: Malyshka, D.,Kuret, J.; Submission name: Cryo-EM visualization of tau aggregation inducer-interaction sites reveals triggers of tau fibrillation and drivers of small-molecule binding; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)