9AUE

Crystal structure of the holo form of GenB2 in complex with PMP

Summary for 9AUE

Entry DOI	10.2210/pdb9aue/pdb
Descriptor	6'-epimerase, C-6' aminotransferase, GLYCEROL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
Functional Keywords	gentamicin biosynthesis, holo form, pyridoxamine-5'-phosphate (pmp), antibiotic
Biological source	Micromonospora echinospora
Total number of polymer chains	1
Total formula weight	45147.91
Authors	Oliveira, G.S.,Bury, P.S.,Huang, F.,Li, Y.,Araujo, N.C.,Zhou, J.,Sun, Y.,Leeper, F.,Leadlay, P.,Dias, M.V.B. (deposition date: 2024-02-29, release date: 2024-09-11, Last modification date: 2024-10-02)
Primary citation	Oliveira, G.S.,Dos S Bury, P.,Huang, F.,Li, Y.,Araujo, N.C.,Zhou, J.,Sun, Y.,Leeper, F.J.,Leadlay, P.F.,Dias, M.V.B. Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis. Acs Chem.Biol., 19:2002-2011, 2024 Cited by PubMed: 39207862 DOI: 10.1021/acschembio.4c00334 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation